The role of serotonin and diet in the prevalence of irritable bowel syndrome: a systematic review

Abstract Serotonin or 5-hydroxytryptamine (5-HT)- a neurotransmitter of both the Enteric Nervous System and Central is synthesized by hydroxylation L- tryptophan to 5-hydroxytryptophan. has been associated with gut functions like assimilation absorption, alongside regulation particle transport fluid discharge in gastrointestinal tract its deficiency found be prominent factor prevalence disorders Irritable Bowel Syndrome. For this review, we assessed conventional treatment methods common drugs, recently accredited options dietary regulation, exercise, meditation, acupuncture. Having that most commonly used drugs exhibited various side effects nausea, fatigue, rash, dizziness, an in-depth evaluation different Indian patterns their respective on levels highlighted formulate ideal diet for patients Syndrome (IBS). This review seeks explore numerous studies conducted link IBS lack serotonin production body, exploring evidence associating certain foods raised hypothesize suitable diet. essence, stresses crucial need further research implications FODMAP (Fermented Oligosaccharides, Disaccharides, Monosaccharides, And Polyols) contents, while underscoring benefits using unconventional natural tryptophan-related disorders.